Progressive trismus in an areca nut chewer
31-year-old male
§Chief complaint
Unable to open the mouth wide and burning on spicy food for 2 years
§Medical & dental history
- 01Chews betel quid with areca nut 8-10 times daily for 10 years
- 02No systemic disease
- 03Difficulty with routine dental treatment due to limited opening
§Clinical examination
- 01Maximum interincisal opening 21 mm
- 02Blanched, marble-white buccal mucosa with palpable vertical fibrous bands bilaterally
- 03Loss of tongue papillae and restricted tongue protrusion
- 04Uvula shrunken; no ulceration or induration
§ figuresFigures (1)
Fig. 1Generalized submucous fibrosis of oral cavity
“Oral submucous fibrosis” · Saivishnu.ponnapalli · CC BY-SA 4.0 · Wikimedia Commons
Verified open-access images only, reproduced for education under their stated licences · no AI-generated or illustrative artwork · Oral Submucous Fibrosis figures pending faculty review.
§Differential diagnosis
§Final diagnosis
Oral submucous fibrosis, clinical stage III
Palpable fibrous bands with mucosal blanching in a long-standing areca nut chewer, without skin involvement or radiation history, is diagnostic. Staging is by mouth opening and functional limitation.
§Investigations
- 01Incisional biopsy — to grade fibrosis and exclude dysplasia or occult carcinoma
- 02Haemoglobin and iron studies
- 03Photographic and interincisal opening records
§Treatment plan
- 01Absolute cessation of areca nut and tobacco
- 02Intralesional corticosteroid and hyaluronidase injections
- 03Supervised physiotherapy with mouth-opening exercises
- 04Surgical band release with grafting if opening remains under 25 mm
§Surgical procedure
- 01Bilateral fibrotic band release with coronoidectomy
- 02Defect covered with buccal fat pad flaps
- 03Aggressive physiotherapy from day 5
§Histopathology report
Atrophic epithelium with loss of rete ridges overlying dense hyalinised, hypovascular collagenous connective tissue with sparse chronic inflammatory cells. No epithelial dysplasia identified.
§Follow-up & outcome
- 01Mouth opening 35 mm at 6 months with continued exercises
- 02Lifelong surveillance — malignant transformation risk 7-13 percent
§Clinical pearls / learning points
- 01OSMF is a potentially malignant disorder; surgery relieves trismus but does not remove cancer risk.
- 02Relapse is almost guaranteed without habit cessation and sustained physiotherapy.
- 03Trismus makes any future oral cancer harder to detect early — examine meticulously.
§References
- Warnakulasuriya S et al. Oral Dis. 2021.
- More CB et al. Classification systems for OSMF.
§Similar cases
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