Case-based Learning

Clinical Case Library

Real-world patient scenarios — history, imaging, differentials, diagnosis, treatment and follow-up.

Case #8820developmental

Cleidocranial Dysplasia

Autosomal dominant skeletal dysplasia with clavicular hypoplasia, delayed cranial ossification, and multiple supernumerary teeth.

HistoryImagingDxFollow-up
Case #8821dental

Dental Caries

Multifactorial biofilm-mediated demineralisation of dental hard tissues by acidogenic bacteria.

HistoryImagingDxFollow-up
Case #8822white-lesions

Leukoplakia

Predominantly white lesion of oral mucosa that cannot be characterised as any other definable lesion. A potentially malignant disorder.

HistoryImagingDxFollow-up
Case #8823red-lesions

Erythroplakia

A red velvety patch that cannot be attributed to any other definable lesion — the highest-risk oral premalignant disorder.

HistoryImagingDxFollow-up
Case #8824ulcerative

Recurrent Aphthous Stomatitis

Recurrent, painful, self-limiting oral ulcers on non-keratinised mucosa in otherwise healthy individuals.

HistoryImagingDxFollow-up
Case #8825vesiculobullous

Pemphigus Vulgaris

Autoimmune intraepithelial blistering disease with IgG autoantibodies against desmoglein-3 (and desmoglein-1).

HistoryImagingDxFollow-up
Case #8826salivary

Sialolithiasis

Calcified concretion within salivary gland ducts; most common disease of salivary glands.

HistoryImagingDxFollow-up
Case #8827fibro-osseous

Fibrous Dysplasia

Benign fibro-osseous lesion in which normal bone is replaced by cellular fibrous tissue with immature woven bone; due to GNAS mutation.

HistoryImagingDxFollow-up
Case #8828odontogenic-cysts

Dentigerous Cyst

Odontogenic developmental cyst that surrounds the crown of an unerupted tooth and is attached at the CEJ.

HistoryImagingDxFollow-up
Case #8829odontogenic-tumors

Ameloblastoma

Benign but locally aggressive odontogenic epithelial tumour; the most common clinically significant odontogenic tumour.

HistoryImagingDxFollow-up
Case #8830premalignant

Oral Submucous Fibrosis

Chronic, progressive, scarring disease of oral mucosa strongly associated with areca nut chewing; a WHO-recognised potentially malignant disorder.

HistoryImagingDxFollow-up
Case #8831oral-cancer

Oral Squamous Cell Carcinoma

Malignant epithelial neoplasm; > 90% of all oral malignancies. Sixth most common cancer worldwide.

HistoryImagingDxFollow-up
Case #8832infections

Ludwig's Angina

Rapidly spreading bilateral cellulitis of the submandibular, sublingual and submental spaces — an airway emergency.

HistoryImagingDxFollow-up
Case #8833trauma

Mandibular Fracture

Most commonly fractured facial bone after nasal bones. Often multiple fractures due to arch geometry.

HistoryImagingDxFollow-up
Case #8834odontogenic-cysts

Radicular Cyst

The most common inflammatory odontogenic cyst; a sequela of pulp necrosis stimulating epithelial cell rests of Malassez at the apex of a non-vital tooth.

HistoryImagingDxFollow-up
Case #8835odontogenic-cysts

Odontogenic Keratocyst

Developmental odontogenic cyst arising from dental lamina remnants; notable for aggressive behaviour, high recurrence, and association with Gorlin–Goltz syndrome.

HistoryImagingDxFollow-up
Case #8836odontogenic-tumors

Odontoma

The most common odontogenic tumour — a hamartomatous developmental malformation of odontogenic tissues classified as compound (denticles) or complex (disorganised mass).

HistoryImagingDxFollow-up
Case #8837odontogenic-tumors

Odontogenic Myxoma

Benign but locally infiltrative odontogenic mesenchymal tumour composed of stellate cells in a myxoid stroma; notable for finger-like invasion of medullary bone and 'tennis-racket' radiographic pattern.

HistoryImagingDxFollow-up
Case #8838non-odontogenic-cysts

Nasopalatine Duct Cyst

The most common non-odontogenic developmental cyst of the oral cavity, arising from epithelial remnants of the embryonic nasopalatine duct within the incisive canal.

HistoryImagingDxFollow-up
Case #8839non-odontogenic-cysts

Nasolabial Cyst

A rare, extra-osseous, developmental soft-tissue cyst of the upper lip and nasal alar base, historically thought to arise from entrapped epithelium of the nasolacrimal duct or the fusion line of embryonic facial processes.

HistoryImagingDxFollow-up
Case #8840non-odontogenic-cysts

Solitary Bone Cyst

A pseudocyst of the jaws lacking an epithelial lining, presenting as an empty or serosanguineous cavity most often in the posterior mandible of adolescents; the leading theory relates to trabecular bone haemorrhage that fails to organise.

HistoryImagingDxFollow-up
Case #8841non-odontogenic-cysts

Aneurysmal Bone Cyst

A rare, rapidly expanding, blood-filled, multilocular pseudocyst of bone — now recognised as a true neoplasm driven by USP6 gene rearrangements — that most commonly involves the posterior mandible of young patients.

HistoryImagingDxFollow-up
Case #8842white-lesions

Oral Lichen Planus

Chronic T-cell mediated mucocutaneous inflammatory disease with characteristic reticular white striae and, in erosive forms, painful ulcerations. Considered an oral potentially malignant disorder.

HistoryImagingDxFollow-up
Case #8843white-lesions

Oral Candidiasis

Opportunistic fungal infection of the oral mucosa, most commonly caused by Candida albicans, presenting as wipeable white plaques (thrush), erythematous patches or angular cheilitis.

HistoryImagingDxFollow-up
Case #8844pigmented

Oral Melanoma

Rare, aggressive malignancy of melanocytes in oral mucosa with poor prognosis.

HistoryImagingDxFollow-up