AtlasInfectionsLudwig's Angina

Maxillofacial Infections

Ludwig's Angina

Rapidly spreading bilateral cellulitis of the submandibular, sublingual and submental spaces — an airway emergency.

§ overviewOverview

Rapidly spreading bilateral cellulitis of the submandibular, sublingual and submental spaces — an airway emergency.

§ etiologyEtiology

  • 01Odontogenic infection from mandibular molars (most common)
  • 02Polymicrobial: streptococci, staphylococci, anaerobes

§ clinicalClinical Features

  • 01Brawny bilateral submandibular swelling
  • 02Raised, protruding, oedematous tongue ('woody floor of mouth')
  • 03Trismus, dysphagia, drooling
  • 04Stridor — impending airway obstruction
  • 05Fever, toxicity

§ investigationsInvestigations

  • 01CBC, CRP, blood culture
  • 02CECT neck — extent and mediastinal spread
  • 03Airway assessment

§ treatmentTreatment

  • 01Airway management is priority — fibre-optic intubation or elective tracheostomy
  • 02IV broad-spectrum antibiotics (Amoxi-clav + metronidazole; add clindamycin/vancomycin for MRSA suspicion)
  • 03Incision & drainage of all involved spaces
  • 04Removal of causative tooth

§ complicationsComplications

  • 01Airway obstruction
  • 02Descending necrotising mediastinitis
  • 03Sepsis
  • 04Cavernous sinus thrombosis

§ prognosisPrognosis

Mortality < 10% with prompt airway control and IV antibiotics.

§ pearlsClinical Pearls

  • 01Airway first, antibiotics second, drainage third.

Draft — pending faculty review. Educational use only; verify against current guidelines and primary sources before clinical application.