Microscopy

Histopathology Atlas

Diagnostic microscope features for the most examined oral lesions.

Slide 001 · H&E

Ameloblastoma — Follicular

· Palisaded columnar cells with reverse polarity
· Stellate reticulum-like centre
· Vickers–Gorlin criteria positive

Slide 002 · H&E

Odontogenic Keratocyst

· 6–8 layer parakeratinised epithelium
· Palisaded basal cells
· Corrugated luminal surface

Slide 003 · H&E

Pleomorphic Adenoma

· Epithelial + myoepithelial cells
· Chondromyxoid stroma
· Encapsulated with pseudopodia

Slide 004 · H&E

Squamous Cell Carcinoma

· Invasive nests of atypical squamous cells
· Keratin pearls (well-diff)
· Nuclear pleomorphism, mitoses

Slide 005 · H&E

Pemphigus Vulgaris

· Suprabasal acantholysis
· Tzanck cells
· Row of tombstones basal cells

Slide 006 · H&E

Fibrous Dysplasia

· Chinese-letter woven bone trabeculae
· No osteoblastic rimming
· Cellular fibrous stroma

Slide 007 · H&E

Central Giant Cell Granuloma

· Multinucleated giant cells
· Vascular fibrous stroma
· Haemosiderin

Slide 008 · H&E

Mucoepidermoid Carcinoma

· Mucous, epidermoid & intermediate cells
· Cystic + solid pattern
· MAML2 fusion

Slide 009 · H&E

Oral Submucous Fibrosis

· Juxtaepithelial hyalinisation
· Atrophic epithelium
· Dysplasia in advanced disease