Bluish floor of mouth swelling with a cervical component
22-year-old female
§Chief complaint
Swelling under the tongue and in the neck for 4 months
§Medical & dental history
- 01Nil relevant
- 02Nil relevant
§Clinical examination
- 01Soft, bluish, translucent swelling of the left floor of mouth elevating the tongue
- 02Painless soft swelling in the left submandibular region, non-tender, no skin change
- 03Wharton duct orifice patent with normal saliva
- 04No trismus or airway compromise
§ figuresFigures (3)
Fig. 1Ranula in a human
“Ranula human 09” · Ph0t0happy · CC BY-SA 3.0 · Wikimedia Commons
Fig. 2Ranula in 55-year-old woman.
“Ranula” · Klaus D. Peter, Wiehl, Germany · CC BY 2.0 de · Wikimedia Commons
Fig. 3Ranula on the floor of the mouth
“Ranula large” · Dikkisherpa5 · CC0 · Wikimedia Commons
Verified open-access images only, reproduced for education under their stated licences · no AI-generated or illustrative artwork · Ranula figures pending faculty review.
§Differential diagnosis
§Final diagnosis
Plunging (cervical) ranula arising from the left sublingual gland
A ranula that extends below the mylohyoid presents as a combined oral and cervical swelling. Being a pseudocyst of extravasated mucus from the sublingual gland, definitive treatment requires removal of that gland, not just the cyst.
§Investigations
- 01Ultrasound neck — anechoic collection extending through the mylohyoid
- 02MRI — high T2 signal 'tail sign' passing posterior to mylohyoid
- 03Aspiration — viscous, mucin-rich fluid with high amylase
§Treatment plan
- 01Excision of the ipsilateral sublingual gland with evacuation of the pseudocyst
- 02Intraoral approach preferred; cervical approach rarely needed
- 03Counsel on lingual nerve and Wharton duct risk
§Surgical procedure
- 01Intraoral floor of mouth incision lateral to the duct
- 02Wharton duct and lingual nerve identified and preserved
- 03Sublingual gland excised, pseudocyst decompressed
- 04No drain; primary closure
§Histopathology report
Mucin pool bounded by granulation tissue without epithelial lining, with adjacent sublingual gland tissue. Consistent with ranula (mucous extravasation pseudocyst).
§Follow-up & outcome
- 01Cervical swelling resolved within 3 weeks
- 02Transient lingual paraesthesia resolved by 6 weeks
- 03No recurrence at 18 months
§Clinical pearls / learning points
- 01Marsupialisation alone has high recurrence; sublingual gland excision is the definitive treatment.
- 02A neck lump with no oral component can still be a plunging ranula — check the amylase in the aspirate.
- 03The lingual nerve crosses under Wharton duct — identify both before dissecting.
§ evidenceReferences & Evidence
Current Classification
WHO Classification of Tumours Online — Head and Neck
IARC / WHO · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Evidence summary
Highest level of evidence linked to this page: WHO / Official Classification.
- L1 · Classification — 1
- L3 · Systematic review — 1
- L6 · Textbook — 3
1 linked source was published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.
Content last reviewed
September 2026
Evidence last reviewed
September 2026
Next scheduled review
September 2027
Review status
EVIDENCE REVIEWED
Search latest PubMed evidence
Last literature search: 7 September 2026
Current Classification
IARC / WHO. IARC · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Systematic Reviews & Meta-Analyses
Kallas-Silva L, Azevedo MFD, de Matos FCM et al.. Brazilian journal of otorhinolaryngology · 2023 · 89(5):101293
Comprehensive review of sialendoscopy for obstructive and inflammatory major salivary gland disease.
Histopathology References
Barnes L. CRC Press · 2008
Detailed histopathological reference for head and neck diagnostic criteria.
Textbook References
Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024
Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.
Rajendran R, Sivapathasundharam B. Elsevier · 2020
Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.
Additional sources cited on this page
- Zhao YF et al. Clinical review of ranula management.
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