Newborn with a unilateral complete cleft lip and palate
0-year-old female
§Chief complaint
Baby born with a split lip and palate, difficulty feeding
§Medical & dental history
- 01Term delivery, birth weight 3.1 kg
- 02No syndromic features; no maternal folate deficiency documented
- 03Neonate, no teeth erupted
§Clinical examination
- 01Complete left unilateral cleft of the lip, alveolus and primary and secondary palate
- 02Deviated columella and flattened left nasal ala
- 03Poor suction with inability to establish a seal at the breast
- 04Ears, hands and heart examination normal; no micrognathia
§ figuresFigures (3)
Fig. 1cleft lip and palate left seen from bottom
“Cleft lip max palate left bot” · Schwing · CC BY-SA 3.0 · Wikimedia Commons
Fig. 2cleft lip and palate both sides seen from bottom
“Cleft lip max palate left right bot” · Schwing · CC BY-SA 3.0 · Wikimedia Commons
Verified open-access images only, reproduced for education under their stated licences · no AI-generated or illustrative artwork · Cleft Lip and Palate figures pending faculty review.
§Differential diagnosis
§Final diagnosis
Non-syndromic complete left unilateral cleft lip and palate
The absence of lower lip pits, micrognathia, airway obstruction or other congenital anomalies points to a non-syndromic cleft. Screening for syndromic associations changes the whole care pathway, so it is done first.
§Investigations
- 01Full neonatal examination and paediatric review with hearing screen
- 02Genetic assessment and counselling for the family
- 03Feeding assessment by the cleft specialist nurse
- 04Serial photographic and impression records
§Treatment plan
- 01Immediate: feeding support with specialised bottles and teats, weight monitoring
- 023 months: cheiloplasty (Millard rotation-advancement) with primary nose correction
- 039-12 months: palatoplasty for speech
- 04Speech and language therapy, audiology, orthodontics through childhood
- 059-11 years: alveolar bone grafting timed to canine root development
- 06Skeletal maturity: orthognathic surgery and rhinoplasty if needed
§Surgical procedure
- 01Cheiloplasty at 3.5 months using rotation-advancement with primary rhinoplasty
- 02Palatoplasty at 10 months with intravelar veloplasty
§Follow-up & outcome
- 01Speech assessed as age-appropriate at 5 years with no velopharyngeal insufficiency
- 02Secondary alveolar bone graft at age 9 with iliac crest cancellous bone; canine erupted through the graft
- 03Orthodontic alignment in progress
§Clinical pearls / learning points
- 01Cleft care is a lifelong multidisciplinary pathway, not a single operation.
- 02Alveolar bone grafting is timed to canine root development (two thirds formed), not to chronological age.
- 03Always examine the lower lip for pits — Van der Woude is the commonest syndromic cleft.
§ evidenceReferences & Evidence
Current Classification
WHO Classification of Tumours Online — Head and Neck
IARC / WHO · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Evidence summary
Highest level of evidence linked to this page: WHO / Official Classification.
- L1 · Classification — 1
- L4 · Research — 1
- L6 · Textbook — 3
1 linked source was published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.
Content last reviewed
September 2026
Evidence last reviewed
September 2026
Next scheduled review
September 2027
Review status
EVIDENCE REVIEWED
Search latest PubMed evidence
Last literature search: 7 September 2026
Current Classification
IARC / WHO. IARC · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Key Research
Mossey PA, Little J, Munger RG et al.. Lancet (London, England) · 2009 · 374(9703):1773-85
Seminar reviewing aetiology, epidemiology and multidisciplinary management of orofacial clefting.
Histopathology References
Barnes L. CRC Press · 2008
Detailed histopathological reference for head and neck diagnostic criteria.
Textbook References
Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024
Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.
Rajendran R, Sivapathasundharam B. Elsevier · 2020
Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.
Additional sources cited on this page
- Royal College of Surgeons / national cleft care standards; Millard DR. Cleft Craft.
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