Malignant Tumors
Osteosarcoma of the Jaw
Malignant mesenchymal tumour producing osteoid; jaw osteosarcoma presents later than long-bone counterparts.
§ figuresFigures (3)
Fig. 1osteosarcoma
“Osteosarcoma mechanism” · Du X, Wei H, Zhang B, Wang B, Li Z, Pang LK, Zhao R, Yao W. · CC BY 4.0 · Wikimedia Commons
Verified open-access images only, reproduced for education under their stated licences · no AI-generated or illustrative artwork · Osteosarcoma of the Jaw figures pending faculty review.
§ overviewOverview
Malignant mesenchymal tumour producing osteoid; jaw osteosarcoma presents later than long-bone counterparts.
§ epidemiologyEpidemiology
3rd–4th decade for jaw (vs 2nd decade for long bones).
§ clinicalClinical Features
- 01Rapidly growing swelling
- 02Paraesthesia (numb chin syndrome — mandibular)
- 03Loose teeth
§ histopathHistopathology
- 01Malignant osteoblasts producing osteoid — osteoblastic, chondroblastic, fibroblastic subtypes
§ radiographicRadiographic Features
- 01Symmetrical widening of PDL space (Garrington's sign)
- 02Sunburst / sunray periosteal reaction
- 03Codman's triangle
§ treatmentTreatment
- 01Radical resection with wide margins + neoadjuvant / adjuvant chemotherapy
- 02Post-op radiotherapy for positive margins
§ prognosisPrognosis
5-year survival 40–60% for jaw osteosarcoma.
§ evidenceReferences & Evidence
Current Classification
WHO Classification of Head and Neck Tumours
5th Edition — Volume 9
WHO Classification of Tumours Editorial Board · 2022
The authoritative international classification of head and neck, odontogenic and salivary gland tumours. Current terminology on this site follows this edition.
Evidence summary
Highest level of evidence linked to this page: WHO / Official Classification.
- L1 · Classification — 2
- L3 · Systematic review — 1
- L6 · Textbook — 3
2 linked sources were published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.
Content last reviewed
September 2026
Evidence last reviewed
September 2026
Next scheduled review
September 2027
Review status
EVIDENCE REVIEWED
Search latest PubMed evidence
Last literature search: 7 September 2026
Current Classification
WHO Classification of Tumours Editorial Board. IARC / World Health Organization · 2022
The authoritative international classification of head and neck, odontogenic and salivary gland tumours. Current terminology on this site follows this edition.
IARC / WHO. IARC · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Systematic Reviews & Meta-Analyses
Zhang L, Guo Y, Sumita Y et al.. International journal of oral and maxillofacial surgery · 2026 · 55(1):10-19
Systematic review of chemotherapy and prognosis in jaw osteosarcoma.
Histopathology References
Barnes L. CRC Press · 2008
Detailed histopathological reference for head and neck diagnostic criteria.
Textbook References
Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024
Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.
Rajendran R, Sivapathasundharam B. Elsevier · 2020
Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.
Draft — pending faculty review. Educational use only; verify against current guidelines and primary sources before clinical application.