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OMFS-0127Soft-tissue lesionsPathologybeginnerMaxillary anterior gingiva

Bleeding gingival mass in pregnancy

27-year-old female

Draft — educational study aid, pending faculty review.

§Chief complaint

Lump on the gum that bleeds when brushing, growing for 6 weeks

§Medical & dental history

  • 0128 weeks pregnant, otherwise well
  • 02Plaque accumulation and gingival inflammation; calculus present

§Clinical examination

  • 01Pedunculated, soft, bright red mass 14 mm on the interdental papilla between 12 and 11
  • 02Bleeds readily on gentle probing
  • 03No bone loss on probing; teeth vital and non-mobile
  • 04No other lesions

§Figures

Verified clinical, radiology and histopathology images not yet available

§Differential diagnosis

Pyogenic granulomaRapidly growing, bleeding, pregnancy, plaque-related
Peripheral giant cell granulomaBluish-purple, may cause cupping bone resorption
Peripheral ossifying fibromaFirmer, arises from the papilla, radiopaque flecks
Metastatic lesion or Kaposi sarcomaRare; consider if risk factors present

§Final diagnosis

Pyogenic granuloma (pregnancy epulis) of the maxillary anterior gingiva

A soft, bright red, easily bleeding pedunculated gingival mass appearing during pregnancy with local plaque irritation is a pyogenic granuloma. A bluish hue with underlying bone cupping would favour a peripheral giant cell granuloma.

§Investigations

  • 01Periapical radiograph — no bone loss or radiopacity within the lesion
  • 02Excisional biopsy after delivery unless symptoms demand earlier removal

§Treatment plan

  • 01Meticulous plaque control and professional scaling — many regress after delivery
  • 02Excision to periosteum with removal of local irritants if it persists or bleeds excessively
  • 03Timing: second trimester or post-partum where possible

§Surgical procedure

  • 01Excision to periosteum with adjacent scaling and root planing under local anaesthesia at 8 weeks post-partum

§Histopathology report

Lobular proliferation of endothelial cells forming numerous small vascular channels in an oedematous stroma with a mixed inflammatory infiltrate and surface ulceration. Lobular capillary haemangioma (pyogenic granuloma).

§Follow-up & outcome

  • 01Complete healing at 3 weeks
  • 02No recurrence at 12 months with maintained oral hygiene

§Clinical pearls / learning points

  • 01Recurrence is due to retained irritants — excise to periosteum and clean the adjacent teeth.
  • 02Not pyogenic and not a granuloma: it is a lobular capillary haemangioma.
  • 03Consider deferring elective excision until after delivery unless bleeding is problematic.

§ evidenceReferences & Evidence

Current Classification

WHO Classification of Tumours Online — Head and Neck

IARC / WHO · 2022

Continuously updated online edition of the WHO head and neck tumour classification.

Evidence summary

Highest level of evidence linked to this page: WHO / Official Classification.

  • L1 · Classification — 1
  • L6 · Textbook — 3

1 linked source was published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.

Content last reviewed

September 2026

Evidence last reviewed

September 2026

Next scheduled review

September 2027

Review status

EVIDENCE REVIEWED

Search latest PubMed evidence

Last literature search: 7 September 2026

Open PubMed

Current Classification

Reference #1L1 · ClassificationWHO / Classification Verified
WHO Classification of Tumours Online — Head and Neck

IARC / WHO. IARC · 2022

Continuously updated online edition of the WHO head and neck tumour classification.

DOI: Identifier not availablePMID: Identifier not available

Histopathology References

Reference #4L6 · TextbookHistopathology References Unverified
Surgical Pathology of the Head and Neck3rd Edition

Barnes L. CRC Press · 2008

Detailed histopathological reference for head and neck diagnostic criteria.

DOI: Identifier not availablePMID: Identifier not available

Textbook References

Reference #2L6 · TextbookTextbooksRecent Verified
Oral and Maxillofacial Pathology5th Edition

Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024

Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.

DOI: Identifier not availablePMID: Identifier not available
Reference #3L6 · TextbookTextbooks Unverified
Shafer's Textbook of Oral Pathology9th Edition

Rajendran R, Sivapathasundharam B. Elsevier · 2020

Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.

DOI: Identifier not availablePMID: Identifier not available

Additional sources cited on this page

  1. Neville BW et al. Oral and Maxillofacial Pathology, 5th ed.

Browse the full evidence library →

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