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OMFS-0218Dentoalveolar traumaTraumaintermediateMaxillary left central incisor (21)

Avulsed permanent incisor replanted after 40 minutes in milk

12-year-old female

Draft — educational study aid, pending faculty review.

§Chief complaint

Front tooth knocked out during a cycling accident

§Medical & dental history

  • 01Healthy; tetanus immunisation current
  • 0221 avulsed, stored in cold milk by a teacher, presented at 40 minutes

§Clinical examination

  • 01Empty socket at 21 with a clot and intact alveolar walls
  • 02Avulsed tooth intact with a closed apex; root surface not scraped
  • 0322 and 11 subluxated, grade I mobile, no displacement
  • 04Lip laceration 8 mm, no foreign bodies

§Figures

Verified clinical, radiology and histopathology images not yet available

§Differential diagnosis

Avulsion (exarticulation) of 21Tooth completely out of the socket
Intrusive luxationTooth driven into bone, may mimic avulsion clinically
Complete alveolar fractureSegment mobile as a block

§Final diagnosis

Avulsion of 21 with a closed apex, extra-oral dry time under 15 minutes and 40 minutes in milk

Short dry time with physiological storage medium gives a realistic chance of periodontal ligament cell survival, so immediate replantation with a flexible splint and later root canal treatment offers the best prognosis.

§Investigations

  • 01IOPA of 11, 21, 22 and occlusal view — exclude root and alveolar fracture, confirm socket integrity
  • 02Confirm tetanus status
  • 03Radiograph of the lip laceration if any fragment is unaccounted for

§Radiology

  • 01IOPA — socket intact, no root fracture; closed apex on 21
  • 02Post-splint radiograph confirms correct seating

§Treatment plan

  • 01Gentle rinse with saline, replant immediately
  • 02Flexible (passive) splint for 2 weeks
  • 03Root canal treatment begun at 7-10 days with calcium hydroxide dressing
  • 04Systemic antibiotics, chlorhexidine rinse, soft diet

§Surgical procedure

  • 01Socket irrigated with saline, clot removed, tooth replanted with gentle digital pressure
  • 02Composite and wire flexible splint 21 to 12 and 22
  • 03Lip laceration sutured with 6-0 resorbable material

§Follow-up & outcome

  • 01Day 10 — root canal treatment initiated, calcium hydroxide placed
  • 02Week 2 — splint removed; tooth firm
  • 033, 6 and 12 months — obturated, no external inflammatory resorption; annual review for 5 years

Outcome: Tooth retained and functional at 2 years with no radiographic resorption.

§Discussion

  • 01Periodontal ligament cell viability is the single determinant of long-term outcome; dry time beyond 60 minutes makes ankylosis and replacement resorption likely.
  • 02Milk, saline, saliva or a cell culture medium are acceptable storage media; water is the worst because it lyses cells.
  • 03In closed-apex teeth, pulp revascularisation does not occur, so root canal treatment is planned from the outset.

§Clinical pearls / learning points

  • 01Hold the tooth by the crown — never scrub the root.
  • 02Flexible splint for 2 weeks; rigid splinting increases ankylosis risk.
  • 03Never replant an avulsed primary tooth.

§Viva questions

What is the ideal storage medium?

A cell culture medium such as Hank's balanced salt solution; cold milk is the practical alternative.

Why start root canal treatment at 7-10 days?

To prevent pulp necrosis driving external inflammatory root resorption, while allowing initial periodontal healing.

§MCQs

Q1The maximum extra-oral dry time compatible with periodontal ligament survival is about:

Q2Recommended splinting for an avulsed tooth is:

§ evidenceReferences & Evidence

Current Classification

WHO Classification of Tumours Online — Head and Neck

IARC / WHO · 2022

Continuously updated online edition of the WHO head and neck tumour classification.

Evidence summary

Highest level of evidence linked to this page: WHO / Official Classification.

  • L1 · Classification — 1
  • L6 · Textbook — 5

1 linked source was published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.

Content last reviewed

September 2026

Evidence last reviewed

September 2026

Next scheduled review

September 2027

Review status

EVIDENCE REVIEWED

Search latest PubMed evidence

Last literature search: 7 September 2026

Open PubMed

Current Classification

Reference #1L1 · ClassificationWHO / Classification Verified
WHO Classification of Tumours Online — Head and Neck

IARC / WHO. IARC · 2022

Continuously updated online edition of the WHO head and neck tumour classification.

DOI: Identifier not availablePMID: Identifier not available

Histopathology References

Reference #6L6 · TextbookHistopathology References Unverified
Surgical Pathology of the Head and Neck3rd Edition

Barnes L. CRC Press · 2008

Detailed histopathological reference for head and neck diagnostic criteria.

DOI: Identifier not availablePMID: Identifier not available

Textbook References

Reference #2L6 · TextbookTextbooksRecent Verified
Oral and Maxillofacial Pathology5th Edition

Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024

Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.

DOI: Identifier not availablePMID: Identifier not available
Reference #3L6 · TextbookTextbooks Unverified
Shafer's Textbook of Oral Pathology9th Edition

Rajendran R, Sivapathasundharam B. Elsevier · 2020

Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.

DOI: Identifier not availablePMID: Identifier not available
Reference #4L6 · TextbookTextbooks Unverified
Contemporary Oral and Maxillofacial Surgery7th Edition

Hupp JR, Ellis E, Tucker MR. Elsevier · 2019

Core surgical textbook covering exodontia, infection, trauma and preprosthetic surgery.

DOI: Identifier not availablePMID: Identifier not available
Reference #5L6 · TextbookTextbooks Unverified
AO Principles of Internal Fixation of the Craniomaxillofacial Skeleton

Ehrenfeld M, Manson PN, Prein J. Thieme / AO Foundation · 2012

Reference standard for craniomaxillofacial trauma osteosynthesis principles and techniques.

DOI: Identifier not availablePMID: Identifier not available

Additional sources cited on this page

  1. International Association of Dental Traumatology Guidelines for avulsion of permanent teeth, 2020.

Browse the full evidence library →

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