Avulsed permanent incisor replanted after 40 minutes in milk
12-year-old female
§Chief complaint
Front tooth knocked out during a cycling accident
§Medical & dental history
- 01Healthy; tetanus immunisation current
- 0221 avulsed, stored in cold milk by a teacher, presented at 40 minutes
§Clinical examination
- 01Empty socket at 21 with a clot and intact alveolar walls
- 02Avulsed tooth intact with a closed apex; root surface not scraped
- 0322 and 11 subluxated, grade I mobile, no displacement
- 04Lip laceration 8 mm, no foreign bodies
§Figures
§Differential diagnosis
§Final diagnosis
Avulsion of 21 with a closed apex, extra-oral dry time under 15 minutes and 40 minutes in milk
Short dry time with physiological storage medium gives a realistic chance of periodontal ligament cell survival, so immediate replantation with a flexible splint and later root canal treatment offers the best prognosis.
§Investigations
- 01IOPA of 11, 21, 22 and occlusal view — exclude root and alveolar fracture, confirm socket integrity
- 02Confirm tetanus status
- 03Radiograph of the lip laceration if any fragment is unaccounted for
§Radiology
- 01IOPA — socket intact, no root fracture; closed apex on 21
- 02Post-splint radiograph confirms correct seating
§Treatment plan
- 01Gentle rinse with saline, replant immediately
- 02Flexible (passive) splint for 2 weeks
- 03Root canal treatment begun at 7-10 days with calcium hydroxide dressing
- 04Systemic antibiotics, chlorhexidine rinse, soft diet
§Surgical procedure
- 01Socket irrigated with saline, clot removed, tooth replanted with gentle digital pressure
- 02Composite and wire flexible splint 21 to 12 and 22
- 03Lip laceration sutured with 6-0 resorbable material
§Follow-up & outcome
- 01Day 10 — root canal treatment initiated, calcium hydroxide placed
- 02Week 2 — splint removed; tooth firm
- 033, 6 and 12 months — obturated, no external inflammatory resorption; annual review for 5 years
Outcome: Tooth retained and functional at 2 years with no radiographic resorption.
§Discussion
- 01Periodontal ligament cell viability is the single determinant of long-term outcome; dry time beyond 60 minutes makes ankylosis and replacement resorption likely.
- 02Milk, saline, saliva or a cell culture medium are acceptable storage media; water is the worst because it lyses cells.
- 03In closed-apex teeth, pulp revascularisation does not occur, so root canal treatment is planned from the outset.
§Clinical pearls / learning points
- 01Hold the tooth by the crown — never scrub the root.
- 02Flexible splint for 2 weeks; rigid splinting increases ankylosis risk.
- 03Never replant an avulsed primary tooth.
§Viva questions
What is the ideal storage medium?
A cell culture medium such as Hank's balanced salt solution; cold milk is the practical alternative.
Why start root canal treatment at 7-10 days?
To prevent pulp necrosis driving external inflammatory root resorption, while allowing initial periodontal healing.
§MCQs
Q1The maximum extra-oral dry time compatible with periodontal ligament survival is about:
Q2Recommended splinting for an avulsed tooth is:
§ evidenceReferences & Evidence
Current Classification
WHO Classification of Tumours Online — Head and Neck
IARC / WHO · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Evidence summary
Highest level of evidence linked to this page: WHO / Official Classification.
- L1 · Classification — 1
- L6 · Textbook — 5
1 linked source was published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.
Content last reviewed
September 2026
Evidence last reviewed
September 2026
Next scheduled review
September 2027
Review status
EVIDENCE REVIEWED
Search latest PubMed evidence
Last literature search: 7 September 2026
Current Classification
IARC / WHO. IARC · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Histopathology References
Barnes L. CRC Press · 2008
Detailed histopathological reference for head and neck diagnostic criteria.
Textbook References
Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024
Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.
Rajendran R, Sivapathasundharam B. Elsevier · 2020
Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.
Hupp JR, Ellis E, Tucker MR. Elsevier · 2019
Core surgical textbook covering exodontia, infection, trauma and preprosthetic surgery.
Ehrenfeld M, Manson PN, Prein J. Thieme / AO Foundation · 2012
Reference standard for craniomaxillofacial trauma osteosynthesis principles and techniques.
Additional sources cited on this page
- International Association of Dental Traumatology Guidelines for avulsion of permanent teeth, 2020.
§Similar cases
81 cases in the library