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OMFS-0220Salivary gland diseasesSalivary GlandbeginnerLeft submandibular gland and Wharton duct

Mealtime swelling of the submandibular gland

41-year-old male

Draft — educational study aid, pending faculty review.

§Chief complaint

Painful swelling under the jaw that appears at mealtimes and settles after an hour

§Medical & dental history

  • 01Well; no xerostomic medication
  • 02Poor fluid intake
  • 03No dental pain; calculus deposits in the lower anterior region

§Clinical examination

  • 01Tender, enlarged left submandibular gland, fluctuating with meals
  • 02Hard palpable stone in the floor of mouth along Wharton duct
  • 03Scanty, cloudy saliva expressed from the left duct orifice
  • 04No skin erythema or systemic upset; bimanual palpation confirms a mobile gland

§ figuresFigures (4)

Fig. 1Salivary gland stone (Sialolithiasis) and the operation marks

“Salivary gland stone removed” · Peternickson · CC0 · Wikimedia Commons

Fig. 2Sialolithiasis, Salivary stones

“Sialolithiasis IMG 2368” · Milorad Dimic MD · CC BY 4.0 · Wikimedia Commons

Verified open-access images only, reproduced for education under their stated licences · no AI-generated or illustrative artwork · Sialolithiasis figures pending faculty review.

§Differential diagnosis

Submandibular sialolithiasis with obstructive sialadenitisMealtime swelling and a palpable duct stone
Duct strictureSame symptoms without a stone; confirmed on sialography or sialendoscopy
Salivary gland tumourPersistent, non-fluctuating mass
Submandibular lymphadenitisNode separate from gland, related to dental or skin infection

§Final diagnosis

Obstructive sialadenitis of the left submandibular gland due to a distal Wharton duct calculus

Classic mealtime syndrome with a palpable radio-opaque stone in the distal duct and a gland that is enlarged but not chronically fibrotic indicates gland-preserving stone removal rather than excision.

§Investigations

  • 01Lower true occlusal radiograph — radio-opaque calculus visible
  • 02Ultrasound to size the stone and assess the gland parenchyma
  • 03Sialendoscopy for diagnosis and treatment if the stone is proximal

§Radiology

  • 01Occlusal radiograph — 8 mm radio-opaque calculus in the distal left Wharton duct
  • 02Ultrasound — dilated duct proximal to the stone, gland parenchyma preserved without abscess

§Treatment plan

  • 01Conservative measures: hydration, sialogogues, gland massage, moist heat
  • 02Transoral removal of the distal stone under local anaesthesia
  • 03Antibiotics only if there is active bacterial sialadenitis
  • 04Gland excision reserved for irreversible parenchymal damage

§Surgical procedure

  • 01Suture placed behind the stone to prevent retro-displacement
  • 02Longitudinal incision over the duct through the floor of mouth mucosa, stone delivered, duct marsupialised rather than closed
  • 03Lingual nerve identified and protected

§Follow-up & outcome

  • 011 week — swelling resolved, clear saliva flowing, tongue sensation normal
  • 023 months — no recurrence of mealtime symptoms
  • 0312 months — gland function preserved on ultrasound

Outcome: Symptom-free with a preserved functioning gland.

§Discussion

  • 01About 80% of salivary calculi occur in the submandibular gland because of the long, upward-running duct and viscous mucinous saliva.
  • 02Minimally invasive options — sialendoscopy, basket retrieval, lithotripsy — have greatly reduced gland excision rates.
  • 03Proximal hilar stones and a fibrotic gland are the usual indications for gland removal.

§Clinical pearls / learning points

  • 01Place a stay suture behind the stone before incising, or it will slip backwards.
  • 02Marsupialise the duct to avoid stricture.
  • 03The lingual nerve crosses the duct — protect it.

§Viva questions

Why are most stones in the submandibular gland?

Longer duct with an uphill course, viscous mucous saliva and higher calcium and phosphate content.

What are the indications for gland excision?

Multiple intraglandular stones, irreversible parenchymal fibrosis, recurrent infections and failed minimally invasive treatment.

§MCQs

Q1The most common site for a salivary calculus is:

Q2Mealtime syndrome refers to:

§ evidenceReferences & Evidence

Current Classification

WHO Classification of Tumours Online — Head and Neck

IARC / WHO · 2022

Continuously updated online edition of the WHO head and neck tumour classification.

Evidence summary

Highest level of evidence linked to this page: WHO / Official Classification.

  • L1 · Classification — 1
  • L3 · Systematic review — 1
  • L6 · Textbook — 3

1 linked source was published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.

Content last reviewed

September 2026

Evidence last reviewed

September 2026

Next scheduled review

September 2027

Review status

EVIDENCE REVIEWED

Search latest PubMed evidence

Last literature search: 7 September 2026

Open PubMed

Current Classification

Reference #1L1 · ClassificationWHO / Classification Verified
WHO Classification of Tumours Online — Head and Neck

IARC / WHO. IARC · 2022

Continuously updated online edition of the WHO head and neck tumour classification.

DOI: Identifier not availablePMID: Identifier not available

Systematic Reviews & Meta-Analyses

Reference #2L3 · Systematic reviewSystematic Reviews & Meta-Analyses Verified
Sialendoscopy for treatment of major salivary glands diseases: a comprehensive analysis of published systematic reviews and meta-analyses

Kallas-Silva L, Azevedo MFD, de Matos FCM et al.. Brazilian journal of otorhinolaryngology · 2023 · 89(5):101293

Comprehensive review of sialendoscopy for obstructive and inflammatory major salivary gland disease.

DOI: 10.1016/j.bjorl.2023.101293PMID: 37487402

Histopathology References

Reference #5L6 · TextbookHistopathology References Unverified
Surgical Pathology of the Head and Neck3rd Edition

Barnes L. CRC Press · 2008

Detailed histopathological reference for head and neck diagnostic criteria.

DOI: Identifier not availablePMID: Identifier not available

Textbook References

Reference #3L6 · TextbookTextbooksRecent Verified
Oral and Maxillofacial Pathology5th Edition

Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024

Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.

DOI: Identifier not availablePMID: Identifier not available
Reference #4L6 · TextbookTextbooks Unverified
Shafer's Textbook of Oral Pathology9th Edition

Rajendran R, Sivapathasundharam B. Elsevier · 2020

Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.

DOI: Identifier not availablePMID: Identifier not available

Additional sources cited on this page

  1. Marchal F, Dulguerov P. Sialolithiasis management. Arch Otolaryngol Head Neck Surg 2003.

Browse the full evidence library →

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