Rapidly spreading neck infection with skin discolouration
58-year-old male
§Chief complaint
Painful neck swelling spreading over 24 hours with dark patches on the skin
§Medical & dental history
- 01Poorly controlled diabetes
- 02Heavy alcohol use
- 03Infected lower left molar for 2 weeks
§Clinical examination
- 01Tense, very painful swelling of the left neck with dusky skin and blisters
- 02Crackling under the skin (crepitus); pain beyond the visible redness
- 03Fever 39.4 C, low blood pressure, confused
§ figuresFigures (3)
Fig. 1The start of Necrotizing Fasciitis in Joe Doetsch.
“Beginning of Necrotizing Fasciitis 01” · Doetsch · CC BY-SA 4.0 · Wikimedia Commons
Verified open-access images only, reproduced for education under their stated licences · no AI-generated or illustrative artwork · Cervicofacial Necrotising Fasciitis figures pending faculty review.
§Differential diagnosis
§Final diagnosis
Cervical necrotising fasciitis of dental origin with septic shock
Rapid spread along the fascia with skin necrosis, gas in tissues and shock is necrotising fasciitis — a surgical emergency confirmed by greyish dead fascia at operation.
§Investigations
- 01Blood tests, lactate, blood cultures
- 02CT neck and chest
- 03Tissue for culture at surgery
§Radiology
- 01CT — gas tracking along the fascia of the neck; no chest spread
§Treatment plan
- 01Resuscitation and intensive care
- 02Broad-spectrum IV antibiotics
- 03Urgent wide removal of all dead tissue, repeated as needed
- 04Removal of the infected tooth; later skin reconstruction
§Surgical procedure
- 01Tracheostomy, wide debridement of dead fascia and skin, extraction of the source tooth, return to theatre at 48 hours
§Histopathology report
Necrotic fascia with blood vessel clots and mixed bacteria. Consistent with necrotising fasciitis.
§Follow-up & outcome
- 01Two further debridements
- 02Week 4 — skin graft
- 03Month 3 — healed, rehabilitation complete
Outcome: Survived after repeated surgery and intensive care, with healed grafted skin.
§Discussion
- 01Death rates remain 20-40%; early surgery is the strongest factor in survival.
§Clinical pearls / learning points
- 01Pain out of proportion with a toxic patient — think necrotising fasciitis and operate early.
§Viva questions
What is the key treatment?
Early and repeated wide surgical debridement with antibiotics and organ support.
§MCQs
Q1A sign strongly suggesting necrotising fasciitis is:
§ evidenceReferences & Evidence
Current Classification
WHO Classification of Tumours Online — Head and Neck
IARC / WHO · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Evidence summary
Highest level of evidence linked to this page: WHO / Official Classification.
- L1 · Classification — 1
- L4 · Research — 1
- L6 · Textbook — 3
2 linked sources were published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.
Content last reviewed
September 2026
Evidence last reviewed
September 2026
Next scheduled review
September 2027
Review status
EVIDENCE REVIEWED
Search latest PubMed evidence
Last literature search: 7 September 2026
Current Classification
IARC / WHO. IARC · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Key Research
R MN, R H, M V et al.. Cureus · 2024 · 16(10):e72337
Review of airway assessment and management strategies in deep neck space infection.
Histopathology References
Barnes L. CRC Press · 2008
Detailed histopathological reference for head and neck diagnostic criteria.
Textbook References
Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024
Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.
Rajendran R, Sivapathasundharam B. Elsevier · 2020
Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.
Additional sources cited on this page
- Gunaratne DA et al. Cervical necrotizing fasciitis: systematic review. Head Neck 2018.
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