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OMFS-0239Rare OMFS casesInfectionadvancedLeft submandibular region and neck

Rapidly spreading neck infection with skin discolouration

58-year-old male

Draft — educational study aid, pending faculty review.

§Chief complaint

Painful neck swelling spreading over 24 hours with dark patches on the skin

§Medical & dental history

  • 01Poorly controlled diabetes
  • 02Heavy alcohol use
  • 03Infected lower left molar for 2 weeks

§Clinical examination

  • 01Tense, very painful swelling of the left neck with dusky skin and blisters
  • 02Crackling under the skin (crepitus); pain beyond the visible redness
  • 03Fever 39.4 C, low blood pressure, confused

§ figuresFigures (3)

Fig. 1The start of Necrotizing Fasciitis in Joe Doetsch.

“Beginning of Necrotizing Fasciitis 01” · Doetsch · CC BY-SA 4.0 · Wikimedia Commons

Verified open-access images only, reproduced for education under their stated licences · no AI-generated or illustrative artwork · Cervicofacial Necrotising Fasciitis figures pending faculty review.

§Differential diagnosis

Cervical necrotising fasciitisSkin necrosis, crepitus, rapid spread, severe illness
Ludwig's anginaFloor of mouth swelling, no skin necrosis
Simple cellulitisNo crepitus, slower, patient less unwell

§Final diagnosis

Cervical necrotising fasciitis of dental origin with septic shock

Rapid spread along the fascia with skin necrosis, gas in tissues and shock is necrotising fasciitis — a surgical emergency confirmed by greyish dead fascia at operation.

§Investigations

  • 01Blood tests, lactate, blood cultures
  • 02CT neck and chest
  • 03Tissue for culture at surgery

§Radiology

  • 01CT — gas tracking along the fascia of the neck; no chest spread

§Treatment plan

  • 01Resuscitation and intensive care
  • 02Broad-spectrum IV antibiotics
  • 03Urgent wide removal of all dead tissue, repeated as needed
  • 04Removal of the infected tooth; later skin reconstruction

§Surgical procedure

  • 01Tracheostomy, wide debridement of dead fascia and skin, extraction of the source tooth, return to theatre at 48 hours

§Histopathology report

Necrotic fascia with blood vessel clots and mixed bacteria. Consistent with necrotising fasciitis.

§Follow-up & outcome

  • 01Two further debridements
  • 02Week 4 — skin graft
  • 03Month 3 — healed, rehabilitation complete

Outcome: Survived after repeated surgery and intensive care, with healed grafted skin.

§Discussion

  • 01Death rates remain 20-40%; early surgery is the strongest factor in survival.

§Clinical pearls / learning points

  • 01Pain out of proportion with a toxic patient — think necrotising fasciitis and operate early.

§Viva questions

What is the key treatment?

Early and repeated wide surgical debridement with antibiotics and organ support.

§MCQs

Q1A sign strongly suggesting necrotising fasciitis is:

§ evidenceReferences & Evidence

Current Classification

WHO Classification of Tumours Online — Head and Neck

IARC / WHO · 2022

Continuously updated online edition of the WHO head and neck tumour classification.

Evidence summary

Highest level of evidence linked to this page: WHO / Official Classification.

  • L1 · Classification — 1
  • L4 · Research — 1
  • L6 · Textbook — 3

2 linked sources were published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.

Content last reviewed

September 2026

Evidence last reviewed

September 2026

Next scheduled review

September 2027

Review status

EVIDENCE REVIEWED

Search latest PubMed evidence

Last literature search: 7 September 2026

Open PubMed

Current Classification

Reference #1L1 · ClassificationWHO / Classification Verified
WHO Classification of Tumours Online — Head and Neck

IARC / WHO. IARC · 2022

Continuously updated online edition of the WHO head and neck tumour classification.

DOI: Identifier not availablePMID: Identifier not available

Key Research

Reference #2L4 · ResearchOriginal ResearchRecent Verified
Navigating the Airway Maze: Challenges and Strategies in Deep Neck Space Infections

R MN, R H, M V et al.. Cureus · 2024 · 16(10):e72337

Review of airway assessment and management strategies in deep neck space infection.

DOI: 10.7759/cureus.72337PMID: 39583498

Histopathology References

Reference #5L6 · TextbookHistopathology References Unverified
Surgical Pathology of the Head and Neck3rd Edition

Barnes L. CRC Press · 2008

Detailed histopathological reference for head and neck diagnostic criteria.

DOI: Identifier not availablePMID: Identifier not available

Textbook References

Reference #3L6 · TextbookTextbooksRecent Verified
Oral and Maxillofacial Pathology5th Edition

Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024

Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.

DOI: Identifier not availablePMID: Identifier not available
Reference #4L6 · TextbookTextbooks Unverified
Shafer's Textbook of Oral Pathology9th Edition

Rajendran R, Sivapathasundharam B. Elsevier · 2020

Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.

DOI: Identifier not availablePMID: Identifier not available

Additional sources cited on this page

  1. Gunaratne DA et al. Cervical necrotizing fasciitis: systematic review. Head Neck 2018.

Browse the full evidence library →

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