Maxillofacial Surgery
Distraction Osteogenesis
aka DO · Callotasis
Gradual mechanical lengthening of bone through an osteotomy that stimulates new bone formation in the distraction gap — powerful for severe hypoplasia.
§ figuresFigures (0)
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Verified open-access images only, reproduced for education under their stated licences · no AI-generated or illustrative artwork · Distraction Osteogenesis figures pending faculty review.
§ overviewOverview
Biological process of new bone formation between vascularised bone segments gradually separated by traction (Ilizarov principle applied to craniofacial skeleton).
§ classificationClassification
- 01By vector: unidirectional, bidirectional, multidirectional
- 02By device: extraoral, intraoral tooth-borne, intraoral bone-borne
- 03By site: mandibular, maxillary, alveolar, midface (RED, Le Fort III)
§ planTreatment Planning
- 01Latency phase 5–7 days
- 02Activation 0.5–1 mm/day (usually 1 mm split into 2 turns)
- 03Consolidation ≥ 2× activation period (8–12 weeks)
- 04Vector planning with 3D CT and stereolithographic models
§ surgicalSurgical Management
- 01Corticotomy preserving medullary blood supply and periosteum
- 02Placement of distractor with correct vector
- 03Rigid fixation; activation begins after latency
§ complicationsComplications
- 01Device failure, screw loosening
- 02Vector deviation, malocclusion
- 03Nerve injury (IAN)
- 04Infection at pin site
- 05Premature consolidation
- 06TMJ ankylosis
§ prognosisPrognosis
Excellent for large advancements (>10 mm) with lower relapse than conventional osteotomy; especially useful in growing patients and syndromic hypoplasia.
§ examKey Examination Points
- 01Confirm vector before activation
- 02Monitor occlusion during activation
- 03Assess IAN function
§ revisionQuick Revision Summary
- 01Latency 5–7 d · rate 1 mm/d · consolidation 2× · Ilizarov principle
§ vivaBDS Viva Questions
- 01What are the phases of DO?
- 02Advantages over conventional osteotomy?
- 03Indications in the maxillofacial region?
§ mcqsMCQs — Assessment (3)
Question 1
Standard activation rate:
Question 2
Consolidation phase relative to activation:
Question 3
Principle originally described by:
§ evidenceReferences & Evidence
Current Classification
WHO Classification of Tumours Online — Head and Neck
IARC / WHO · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Evidence summary
Highest level of evidence linked to this page: WHO / Official Classification.
- L1 · Classification — 1
- L3 · Systematic review — 1
- L6 · Textbook — 4
1 linked source was published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.
Content last reviewed
September 2026
Evidence last reviewed
September 2026
Next scheduled review
September 2027
Review status
EVIDENCE REVIEWED
Search latest PubMed evidence
Last literature search: 7 September 2026
Current Classification
IARC / WHO. IARC · 2022
Continuously updated online edition of the WHO head and neck tumour classification.
Systematic Reviews & Meta-Analyses
Wang M, Zhang B, Li L et al.. European journal of orthodontics · 2022 · 44(1):1-10
Systematic review of vertical skeletal stability across orthognathic treatment protocols.
Histopathology References
Barnes L. CRC Press · 2008
Detailed histopathological reference for head and neck diagnostic criteria.
Textbook References
Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024
Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.
Rajendran R, Sivapathasundharam B. Elsevier · 2020
Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.
Hupp JR, Ellis E, Tucker MR. Elsevier · 2019
Core surgical textbook covering exodontia, infection, trauma and preprosthetic surgery.
Additional sources cited on this page
- McCarthy JG. Plast Reconstr Surg 1992
Draft — pending faculty review. Educational use only; verify against current guidelines and primary sources before clinical application.