AtlasSurgeryDistraction Osteogenesis

Maxillofacial Surgery

Distraction Osteogenesis

aka DO · Callotasis

Gradual mechanical lengthening of bone through an osteotomy that stimulates new bone formation in the distraction gap — powerful for severe hypoplasia.

Rate
1 mm/day
Latency
5–7 d
Consolidation
≥2× activation

§ figuresFigures (0)

Verified clinical image not yet available

Verified open-access images only, reproduced for education under their stated licences · no AI-generated or illustrative artwork · Distraction Osteogenesis figures pending faculty review.

§ overviewOverview

Biological process of new bone formation between vascularised bone segments gradually separated by traction (Ilizarov principle applied to craniofacial skeleton).

§ classificationClassification

  • 01By vector: unidirectional, bidirectional, multidirectional
  • 02By device: extraoral, intraoral tooth-borne, intraoral bone-borne
  • 03By site: mandibular, maxillary, alveolar, midface (RED, Le Fort III)

§ planTreatment Planning

  • 01Latency phase 5–7 days
  • 02Activation 0.5–1 mm/day (usually 1 mm split into 2 turns)
  • 03Consolidation ≥ 2× activation period (8–12 weeks)
  • 04Vector planning with 3D CT and stereolithographic models

§ surgicalSurgical Management

  • 01Corticotomy preserving medullary blood supply and periosteum
  • 02Placement of distractor with correct vector
  • 03Rigid fixation; activation begins after latency

§ complicationsComplications

  • 01Device failure, screw loosening
  • 02Vector deviation, malocclusion
  • 03Nerve injury (IAN)
  • 04Infection at pin site
  • 05Premature consolidation
  • 06TMJ ankylosis

§ prognosisPrognosis

Excellent for large advancements (>10 mm) with lower relapse than conventional osteotomy; especially useful in growing patients and syndromic hypoplasia.

§ examKey Examination Points

  • 01Confirm vector before activation
  • 02Monitor occlusion during activation
  • 03Assess IAN function

§ revisionQuick Revision Summary

  • 01Latency 5–7 d · rate 1 mm/d · consolidation 2× · Ilizarov principle

§ vivaBDS Viva Questions

  • 01What are the phases of DO?
  • 02Advantages over conventional osteotomy?
  • 03Indications in the maxillofacial region?

§ mcqsMCQs — Assessment (3)

Question 1

Standard activation rate:

Question 2

Consolidation phase relative to activation:

Question 3

Principle originally described by:

§ evidenceReferences & Evidence

Current Classification

WHO Classification of Tumours Online — Head and Neck

IARC / WHO · 2022

Continuously updated online edition of the WHO head and neck tumour classification.

Evidence summary

Highest level of evidence linked to this page: WHO / Official Classification.

  • L1 · Classification — 1
  • L3 · Systematic review — 1
  • L6 · Textbook — 4

1 linked source was published from 2024 onwards. Where guidance is limited or contested, rely on the higher-level sources above rather than this summary. Educational use only — not a substitute for clinical judgement.

Content last reviewed

September 2026

Evidence last reviewed

September 2026

Next scheduled review

September 2027

Review status

EVIDENCE REVIEWED

Search latest PubMed evidence

Last literature search: 7 September 2026

Open PubMed

Current Classification

Reference #1L1 · ClassificationWHO / Classification Verified
WHO Classification of Tumours Online — Head and Neck

IARC / WHO. IARC · 2022

Continuously updated online edition of the WHO head and neck tumour classification.

DOI: Identifier not availablePMID: Identifier not available

Systematic Reviews & Meta-Analyses

Reference #2L3 · Systematic reviewSystematic Reviews & Meta-Analyses Verified
Vertical stability of different orthognathic treatments for correcting skeletal anterior open bite: a systematic review and meta-analysis

Wang M, Zhang B, Li L et al.. European journal of orthodontics · 2022 · 44(1):1-10

Systematic review of vertical skeletal stability across orthognathic treatment protocols.

DOI: 10.1093/ejo/cjab011PMID: 33822036

Histopathology References

Reference #6L6 · TextbookHistopathology References Unverified
Surgical Pathology of the Head and Neck3rd Edition

Barnes L. CRC Press · 2008

Detailed histopathological reference for head and neck diagnostic criteria.

DOI: Identifier not availablePMID: Identifier not available

Textbook References

Reference #3L6 · TextbookTextbooksRecent Verified
Oral and Maxillofacial Pathology5th Edition

Neville BW, Damm DD, Allen CM et al.. Elsevier · 2024

Standard reference textbook of oral and maxillofacial pathology used throughout this atlas.

DOI: Identifier not availablePMID: Identifier not available
Reference #4L6 · TextbookTextbooks Unverified
Shafer's Textbook of Oral Pathology9th Edition

Rajendran R, Sivapathasundharam B. Elsevier · 2020

Undergraduate and postgraduate oral pathology textbook widely used in BDS and FCPS curricula.

DOI: Identifier not availablePMID: Identifier not available
Reference #5L6 · TextbookTextbooks Unverified
Contemporary Oral and Maxillofacial Surgery7th Edition

Hupp JR, Ellis E, Tucker MR. Elsevier · 2019

Core surgical textbook covering exodontia, infection, trauma and preprosthetic surgery.

DOI: Identifier not availablePMID: Identifier not available

Additional sources cited on this page

  1. McCarthy JG. Plast Reconstr Surg 1992

Browse the full evidence library →

Draft — pending faculty review. Educational use only; verify against current guidelines and primary sources before clinical application.